Questionnaires & surveys for research are dead.

Today, I'm gonna make a prediction, and that prediction is that within five years, you won't be able to publish clinical research in leading journals if it uses questionnaires or subjective patient reported outcomes.

Full Transcript:

Welcome to Storyline, where our mission is to understand human behavior and make that knowledge useful for everyone. My name's Christopher Greg.

I'm the CSO at Storyline Health, and I'm also an associate professor of neurobiology at the University of Utah. Today, I'm gonna make a prediction, and that prediction is that within five years, you won't be able to publish clinical research in leading journals if it uses questionnaires or subjective patient reported outcomes.

These are really common in the clinical research fields, and I really think their days are numbered, and I think their days are not just numbered in scientific publications, but also soon after that it will be very difficult to get through the FDA using these types of approaches for measuring outcomes.

The signals that this is happening are already coming out of the basic research field, which has shifted to objective computational and AI methods for doing behavioral analysis and symptom phenotyping in animal models is a whole series of different high profile publications that have come out. Some are from our lab that are contributing to this shift from towards more computational and unbiased methods for quantifying phenotypes. And storyline now makes this possible for massively scalable human clinical studies.

So there is now a real opportunity to shift, to use these extraordinary tools in clinical research to do much more objective, sensitive, precise research of symptoms in patient behavior. So that means no more of these overly simplified and overly broad questionnaires, and even those overly simplified and overly broad DSM five diagnostic categories.

These are going to be replaced very quickly with more objective data driven and scalable measures. Storyline enables you to capture and measure over 20,000 different micro features from human behavior expressed and captured on a smartphone.

Through the video components. We can measure things like pupil dilation and eye tracking and perfusion and blood flow patterns across the face, micro-expressions, motor patterns, and much, much more from the speech.

We analyze what people say and how they articulate their responses, the sentiment that they are expressing, the words that they use and the patterns that are embedded within the speech that they articulate in responding to different answers. And then it's not just what you say but how you say it. And That's why we also measure the audio.

We capture thousands and thousands of features out of the audio that detect emotion in the voice, stress in the voice, tremors in the voice, and much, much more information.

So that's really exciting because using these more objective approaches rather than questionnaires, we can build powerful diagnostic models that are driven by non-linear interactions between thousands and thousands and thousands of measures that build very, very accurate classifiers and I should say classifiers for different disorders or phenotypes of interest there.

And this means that massively scalable precision medicine is now possible. It's data driven, it's objective, it's sensitive, it's precise, and it's secure, and the word is out.

There's many people now using storyline in a variety of different studies that range from cancer to Alzheimer's to addiction, to suicide risk and many, many more mental illness drug responses. The list goes on and on.

We're so excited about this revolution. We wanna get the word out. And so that's what these videos are all about.

Please try storyline out. You can try it for free by just going to the website, signing up for a free account, or reach out to us and get a demo. Let us show you what you can do, and you'll be surprised the the capabilities that storyline has are truly, truly transformative.

Thank you.